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KMID : 0387720220330020107
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Korean Journal of Blood Transfusion
2022 Volume.33 No. 2 p.107 ~ p.113
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Three Cases of SARS-CoV-2 Infection with Cold Antibody of Undetermined Specificity in Antibody Screening in Transfusion Labs
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Kim Beom-Joon
Shin Dong-Woo
Hong Yun-Ji
Kim Hyung-Suk
Park Kyoung-Un
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Abstract
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SARS-CoV-2 infections continue to occur in this worldwide pandemic and have been associated with various symptoms, including autoimmune disorders. Of the latter, several reports of SARS-CoV-2-associated cold-agglutinin syndrome (CAS) have been published. CAS is associated with other viral infections, such as that by the Epstein?Barr virus. This paper reports a case series of SARS-CoV-2-associated cold-agglutinin syndrome presenting as an antibody of undetermined specificity mainly reactive at cold temperatures and mostly detected as C3d, but sometimes as IgM on the direct antiglobulin test.
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KEYWORD
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Cold agglutinin disease, SARS-CoV-2, Autoantibody
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